"The stigma of HIV-infection may profoundly affect the lives of persons living with HIV/AIDS (PLHA). However few studies have examined the association of HIV stigma with multiple components of HIV treatment and care," scientists in the United States report (see also HIV/AIDS).

"To estimate the association between HIV stigma and: self-reported access to care, regular source of HIV care, and antiretroviral therapy adherence; and to test whether mental health mediates these associations. Cross-sectional study. 202 PLHA living in Los Angeles County in 2007. Participants completed an anonymous survey, assessing internalized HIV stigma (28-items, alpha = 0.93), self-reported access to medical care (six items, alpha = 0.75), regular source of HIV care, and antiretroviral therapy (ART) adherence. One-third of participants reported high levels of stigma; 77% reported poor access to care; 42.5% reported suboptimal ART adherence; and 10.5% reported no regular source of HIV care. In unadjusted analysis, those reporting a high level of stigma were more likely to report poor access to care (OR=4.97, 95% CI 2.54-9.72), regular source of HIV care (OR= 2.48, 95% CI 1.00-6.19), and ART adherence (OR= 2.45, 95% CI 1.23-4.91). In adjusted analyses, stigma was significantly associated with poor access to care (OR=4.42, 95% CI 1.88-10.37), but not regular source of HIV care or ART adherence. Mental health mediated the relationship between stigma and ART adherence, but not poor access to care or regular source of HIV care," wrote J.N. Sayles and colleagues, University of California.

The researchers concluded: "The association of stigma with self-reported access to care and adherence suggests that efforts to improve these components of HIV care will require a better understanding of the possible effects of stigma and it's mediators."

Sayles and colleagues published their study in the Journal of General Internal Medicine (The Association of Stigma with Self-Reported Access to Medical Care and Antiretroviral Therapy Adherence in Persons Living with HIV/AIDS. Journal of General Internal Medicine, 2009;24(10):1101-1108).

For additional information, contact J.N. Sayles, University of California, Division General Internal Medicine & Health Service Research, David Geffen School Medical, Los Angeles, CA 90024, USA.

The publisher's contact information for the Journal of General Internal Medicine is: Springer, 233 Spring St., New York, NY 10013, USA.